主讲人简介：

Martin F. Jarrold is Distinguished Professor Emeritus and Robert & Marjorie Mann Chair of Chemistry at Indiana University. He is an internationally recognized physical and analytical chemist and the inventor of ELIT-based charge detection mass spectrometry (CDMS), which extends mass spectrometry to extremely large and heterogeneous systems. He received his B.Sc. in Molecular Sciences in 1977 and his Ph.D. in Chemistry in 1980 from the University of Warwick, followed by postdoctoral work at the University of California, Santa Barbara, and research at AT&T Bell Laboratories. He made pioneering contributions to ion mobility theory and high-resolution CDMS, enabling accurate analysis of viruses, viral vectors, vaccines, lipoproteins, and nanoparticles. He has authored more than 280 peer-reviewed publications and helped drive the commercialization of CDMS instrumentation.

讲座内容简介：

传统质谱在分析高质量、强异质性的样品时，常受到电荷态重叠和质量解析能力不足的限制。电荷检测质谱（CD-MS）通过对单个离子的质荷比和电荷进行同步测量，可直接获得病毒、病毒样颗粒、基因治疗载体、疫苗及纳米颗粒等复杂样品的质量分布。本报告将介绍CD-MS的基本原理、技术演进与最新仪器发展，重点展示其在超大分子和高异质性体系精确表征中的优势，并结合商业化CD-MS平台的推出，讨论该技术在生物治疗产品质量评价、纳米材料表征与病毒分析中的应用前景。